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Frontiers | Mitochondrial dysfunction in diabetic nephropathy: insights and therapeutic avenues from traditional Chinese medicine
It was recently found that BHB-mediated P53 Kbhb inhibits the level of p53 acetylation and reduces the transcriptional activity of p53 on typical p53 target genes (including p21 and PUMA), thereby reducing the effect of p53 on apoptosis and cell growth (37)
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