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Additionally, SIRT6 induces the expression of GATA-binding protein 5 (GATA5, a novel blood pressure regulator) and regulates the GATA5-mediated signaling pathway to prevent hypertension and its complications caused by endothelial dysfunction and improve apoptosis and mitochondrial dysfunction induced by Ang II (Guo et al., 2019)

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At equal molar concentrations (based on the optimized amount for DDA), we found that both C10 and C12 (DDA) are equivalent and both induced a facile phase transfer while C4 did not