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CyRL-QN15 adds targeted inflammatory modulation and hair follicle regeneration via miRNA and Wnt/β-catenin pathways [86, 87]

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Although there are currently no large-scale clinical trials of DPP1 inhibitors specifically for COPD, based on positive results in bronchiectasis studies and mechanism of action analysis, DPP1 inhibitors are expected to provide new treatment options for COPD patients, particularly those with neutrophil inflammation as the main characteristic phenotype may achieve more significant therapeutic benefits