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perform test dose prior to therapeutic use to confirm appropriate coagulation profile response Neurohypophyseal diabetes insipidus: (DDAVP(R)) 10 to 40 mcg/day (0.1 mL to 0.4 mL) INTRANASALLY, either as a single dose or 2 to 3 divided doses Neurohypophyseal diabetes insipidus 2 to 4 mcg/day IV or SUBQ in 2 divided doses