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Figure 8 3.4.5 Interactive crosstalk among airway structural cells, immune cells, and central and peripheral neurons Psychological stress and negative emotions like pain and depression can promote bronchoconstriction and increased airway inflammation, contributing to asthma exacerbation and poor control of asthma symptoms ( Psychological stress exacerbates asthma via brain-lung axis crosstalk, engaging CNS components through established neural and humoral pathways
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While serum levels begin to rise within days, the clinical resolution of symptoms—such as fatigue, bone pain, or muscle weakness—often occurs within 2 to 4 weeks as the body replenishes its cellular stores
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