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It is possible that spinnability, or the tendency of CF mucus to form adherent threads, could be a factor influencing the efficacy of ARINA-1 independent of mucus hydration, as also shown for hypertonic saline (44)

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The absorbance at 490 nm was measured and the concentration of FITC-labeled dextran was calculated from the standard curve for the upper and lower chambers in each group before calculating the penetration rate