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5 Once steady state is reached, the washout period † for AJOVY is similar for monthly and quarterly dosing (~5-6 half-lives) 6 † Washout period defined as time until plasma concentrations of AJOVY are below a clinically relevant concentration and thus considered eliminated

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The exact mechanism isn't fully mapped out, but it's thought to involve minoxidil sulfate (the active metabolite produced when minoxidil is converted in the body) interacting with follicle cells to delay the transition from anagen to the resting phase