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Next ADCC activity against cell lines expressing low (WSU-NHL and Carnaval) or high (SU-DHL-4) levels of CD20 was measured in presence of anti-CD20 mAb2 IgG1 variants using human mononuclear cells (MNCs) in a 51 Cr release assay 50 (Fig
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In addition, IL-10 can activate mast cells and strengthen the functions of CD8 + T, B, and NK cells
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