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Upon activation, these cells undergo metabolic reprogramming, which subsequently yields diverse functional outcomes
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There are two main forms of Grx: Grx1 is found in the cytoplasm and accepts electrons from GSH, whereas Grx2 is located in the mitochondria and nucleus of mammalian cells and can obtain electrons from GSH and TrxR2 (Fernandes and Holmgren, 2004)
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