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Serum holoTC is a better biomarker of recent B12 intake than serum B12 (or methymalonic acid or tHcy) because serum holoTC concentrations increase much faster after ingestion of B12 from a meal (i.e., 6 hours) or crystalline B12 from supplements
homocysteine
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For this compound the honest answer is always a mouse, and the bioavailability figure is the one least likely to be quoted at all
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