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However in most clinical trials or studies using melatonin, it is well accepted that in general melatonin lacks toxic adverse events, and it is a safe drug at most of the usual tested doses from 0.5 to 5 mg/d (118)

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10.1042/ebc20160079 [DOI] [PubMed] [Google Scholar] Vajrychova M, Salovska B, Pimkova K et al (2019) Quantification of cellular protein and redox imbalance using SILAC-iodoTMT methodology