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Exclusion criteria were as follows: (I) patients with chronic diseases that may affect hematologic parameters (sideroblastic anemia, thalassemia, aplastic anemia, etc.), (II) folate deficiency, (III) iron deficiency, (IV) renal disease, (V) using drugs that may affect the absorption of VB12 (metformin, proton pump inhibitors, phenobarbital, etc.), and (VI) having missing data