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The cytoprotective and prosurvival role of autophagy in CP-induced AKI has been proved in many pharmacological and Atg-gene knockout studies (Periyasamy-Thandavan et al., 2008
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On the other hand, a well-controlled ET patient (platelets in safer range, perhaps on aspirin or hydroxyurea) or a PV patient who just underwent phlebotomy and is on stable therapy might be considered moderate risk
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