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doi: 10.1016/j.tins.2009.05.009
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S -glutathionylation of eNOS is thought to be a pivotal switch providing redox regulation of cellular signaling, endothelial function, and vascular tone.86 Furthermore, while uncoupling of eNOS leads to potent inactivation of NO through its reaction with superoxide (O 2 − ), this reaction forms the potent oxidant peroxynitrite (ONOO − ) (Figure 1)
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