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After classification using a supervised random-forest model, benchmarked CR-I and CR-P values corresponding to stages 1–3 were calculated (Fig

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In the STEP-4 randomized trial (Rubino and colleagues, JAMA, 2021), the 803 adults who switched to placebo at week 20 regained about 6.9 percent of body weight over the next 48 weeks, while those who continued semaglutide kept losing