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However, under pathological or stressful conditions, oxidative modifications of Hb through metHb or hemichrome formation not only impair its O 2 -carrying capacity but also trigger membrane damage, protein aggregation, and RBC senescence [170]

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Diffractaic acid, a novel TrxR1 inhibitor, induces cytotoxicity, apoptosis, and antimigration in human breast cancer cells

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