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According to their study, superoxide and peroxynitrite contribute to inflammatory and neuropathic pain by central sensitization and increased peripheral sensitivity (Salvemini et al., 2011)

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For example, as explained in a 2024 review, people with premenstrual dysphoric disorder (PMDD) typically have normal female hormone levels throughout their menstrual cycle.16 With that being said, the breakdown below details some of the ways female hormone changes — including imbalances and natural fluctuations — can uniquely impact the health of AFAB individuals